Modern medicine explains this phenomenon through autonomic nervous system imbalance. The autonomic nervous system is divided into sympathetic nerves and parasympathetic nerves. The sympathetic nerve prepares our body for fight or flight during danger, quickening the heart rate, raising blood pressure, and tensing muscles. When this sympathetic nerve is activated, the activity of the salivary glands is suppressed. Xerostomia, where the mouth completely dries up, is one of the classic symptoms that appears when sympathetic nerves become excessively elevated during stress.
Our salivary glands are primarily controlled by parasympathetic nerves and actively secrete saliva during calm states. When sympathetic nerves become dominant due to stress, blood flow volume to the salivary glands decreases, and saliva becomes thicker while its volume drops. Rather than a simple lack of moisture, the stress response directly affects salivary gland function. Furthermore, chronic stress hyperactivates our body's stress response axis, the hypothalamic-pituitary-adrenal axis. Sustained activity in this axis leads to excessive secretion of the stress hormone cortisol, which circulates systemically and further disrupts autonomic nervous system balance. High cortisol levels affect the immune system and can trigger chronic inflammation responses, which in turn can impair salivary gland function.
Mental health concerns such as anxiety, tension, and panic attacks are also closely tied to xerostomia. People experiencing anxiety or panic attacks are placed under extreme stress, causing sympathetic nerves to surge more fiercely, which can lead to severe xerostomia. Struggling to breathe and experiencing heart palpitations while the mouth goes dry doubles the distress. In addition, xerostomia harms oral health. Saliva cleanses the oral cavity, removes food debris, neutralizes acids, and provides antibacterial actions. When saliva dries up, dental caries, gum disease, and halitosis develop, and the oral cavity mucosa dries out, creating an environment prone to inflammation. Without care, this can spiral into a vicious cycle.
This autonomic nervous system imbalance does not merely affect the salivary glands; it impacts organs throughout the body, including the digestive system, cardiovascular system, and endocrine system. In other words, xerostomia serves as an important warning sign showing how stress is disrupting our entire body. Just as Donguibogam explained body fluids as our living water and lubricant, modern medicine emphasizes that saliva is not a simple liquid, but a cornerstone of immunity, digestion, and oral cavity health. Beyond simply drinking plenty of water, it is important to reflect on the value of managing stress and restoring autonomic nervous system balance.
The modern lifestyle places even greater strain on this autonomic nervous system. Sleep deprivation, excessive caffeine intake, irregular meals, and relentless information overload all stimulate sympathetic nerves, much like keeping a foot pressed down on a car's accelerator. Eventually, the parasympathetic nerve, which acts as the brake, loses its proper function and becomes exhausted. When this state persists, it manifests as various physical symptoms such as dyspepsia, chronic fatigue, headache, and insomnia, alongside xerostomia. We must pay attention to these subtle signals from the body and explore the root causes behind them, as each symptom may be a quiet cry for help from within.